![C41H51N5O8Si Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)- (9CI, ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C41H51N5O8SI guanosine, 5′-O- [bis (4-methoxyphenyl) fenilmetil] -2′-O-[(1,1- dimethylethyl) dimethylsilyl] -n- (2-methyl-1-oxopropyl)-(9CI, ACI), ACI), ACI)-(9CI, ACI), ACI)-(ACI), ACI-METHYL-1-OXOPROPYL)-](https://cdn.globalso.com/nvchem/C41H51N5O8Si-Guanosine.jpg)
C41H51N5O8Si Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)- (9CI, ACI)
| Kle pwopriyete fizik | Valè | Kondisyon |
| Pwa molekilè | 769.96 | - |
| Dansite (prevwa) | 1.25 ± 0.1 g/cm3 | Tanperati: 20 ° C; Peze: 760 Torr |
| PKA (prevwa) | 9.16 ± 0.20 | Pifò asid tanperati: 25 ° C |
Souri kanonyal o = c1n = c (nc (= o) c (c) c) nc2 = c1n = cn2c3oc (coc (c = 4c = cc = cc4) (c5 = cc = c (oc) c = c5) c6 = c = c (oc) c = c) c (o) c3O [Si]
Souri izomèr
C (OC [C@H] 1O [C@H] ([C@H] (O [SI] (C (C) (C) C) (C) C) [C @@ H] 1O) N2C3 = C (N = C2) C ( = O) n = c (nc (c (c) c) = o) n3) (c4 = cc = c (oc) c = c4)
Inchi
Inchi = 1S/C41H51N5O8SI/C1-25 (2) 36 (48) 44-39-43-35-32 (37 (49) 45-39 ) 42-24-46 (35) 38-34 (54-55 (8,9) 40 (3,4) 5) 33 (47) 31 (53-38) 23-52-41 (2 6-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,
48,49)/T31-, 33-, 34-, 38-/m1/s1
Inchi kle
Jmcnkjfoijgyrg-cjegosrcsa-n
1 lòt non pou sibstans sa a
5′-O-
Spèktr ki disponib
1H NMR
13c NMR
Mas
| Pwopriyete ki disponib |
| Biolojik |
| Chimik |
| Densite |
| Lipinski |
| Estrikti ki gen rapò |
Biolojik
| Posesyon | Valè | Kondisyon | Sous |
| Faktè bioconcentration | 1.38 x 105 | Ph 1; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 3.53 x 105 | pH 2; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 4.18 x 105 | pH 3; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 4.26 x 105 | pH 4; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 4.26 x 105 | pH 5; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 4.26 x 105 | pH 6; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 4.21 x 105 | pH 7; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 3.77 x 105 | pH 8; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 1.86 x 105 | pH 9; Tan: 25 ° C | (1) ACD |
| Faktè bioconcentration | 33800 | pH 10; Tan: 25 ° C | (1) ACD |
(1) Kalkile lè l sèvi avèk avanse Chimi Devlopman (ACD/Labs) lojisyèl v11.02 (© 1994-2023 ACD/Labs)
Chimik
| Posesyon | Valè | Kondisyon | Sous |
| Ka | 1.21 x 105 | Ph 1; Tan: 25 ° C | (1) ACD |
| Ka | 3.08 x 105 | pH 2; Tan: 25 ° C | (1) ACD |
| Ka | 3.65 x 105 | pH 3; Tan: 25 ° C | (1) ACD |
| Ka | 3.72 x 105 | pH 4; Tan: 25 ° C | (1) ACD |
| Ka | 3.73 x 105 | pH 5; Tan: 25 ° C | (1) ACD |
| Ka | 3.72 x 105 | pH 6; Tan: 25 ° C | (1) ACD |
| Ka | 3.68 x 105 | pH 7; Tan: 25 ° C | (1) ACD |
| Posesyon | Valè | Kondisyon | Sous |
| Ka | 3.30 x 105 | pH 8; Tan: 25 ° C | (1) ACD |
| Ka | 1.62 x 105 | pH 9; Tan: 25 ° C | (1) ACD |
| Ka | 29600 | pH 10; Tan: 25 ° C | (1) ACD |
| Logd | 7.22 | Ph 1; Tan: 25 ° C | (1) ACD |
| Logd | 7.63 | pH 2; Tan: 25 ° C | (1) ACD |
| Logd | 7.70 | pH 3; Tan: 25 ° C | (1) ACD |
| Logd | 7.71 | pH 4; Tan: 25 ° C | (1) ACD |
| Logd | 7.71 | pH 5; Tan: 25 ° C | (1) ACD |
| Logd | 7.71 | pH 6; Tan: 25 ° C | (1) ACD |
| Logd | 7.70 | pH 7; Tan: 25 ° C | (1) ACD |
| Logd | 7.66 | pH 8; Tan: 25 ° C | (1) ACD |
| Logd | 7.35 | pH 9; Tan: 25 ° C | (1) ACD |
| Logd | 6.61 | pH 10; Tan: 25 ° C | (1) ACD |
| logp | 7.710 ± 0.709 | Tan: 25 ° C | (1) ACD |
| Mas solubilite intrinsèques | 2.7 x 10-5 g/l | Tan: 25 ° C | (1) ACD |
| Mas solubility | 8.5 x 10-5 g/l | Ph 1; Tan: 25 ° C | (1) ACD |
| Mas solubility | 3.3 x 10-5 g/l | pH 2; Tan: 25 ° C | (1) ACD |
| Mas solubility | 2.8 x 10-5 g/l | pH 3; Tan: 25 ° C | (1) ACD |
| Mas solubility | 2.7 x 10-5 g/l | pH 4; Tan: 25 ° C | (1) ACD |
| Mas solubility | 2.7 x 10-5 g/l | pH 5; Tan: 25 ° C | (1) ACD |
| Mas solubility | 2.7 x 10-5 g/l | pH 6; Tan: 25 ° C | (1) ACD |
| Mas solubility | 2.8 x 10-5 g/l | pH 7; Tan: 25 ° C | (1) ACD |
| Mas solubility | 3.1 x 10-5 g/l | pH 8; Tan: 25 ° C | (1) ACD |
| Mas solubility | 6.2 x 10-5 g/l | pH 9; Tan: 25 ° C | (1) ACD |
| Mas solubility | 3.5 x 10-4 g/l | pH 10; Tan: 25 ° C | (1) ACD |
| Mas solubility | 2.8 x 10-5 g/l | PH dlo unbuffered 7.00; Tan: 25 ° C | (1) ACD |
| Molar intrinsèques solubility | 3.5 x 10-8 mol/l | Tan: 25 ° C | (1) ACD |
| Solubilite molè | 1.1 x 10-7 mol/l | Ph 1; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 4.3 x 10-8 mol/l | pH 2; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 3.6 x 10-8 mol/l | pH 3; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 3.5 x 10-8 mol/l | pH 4; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 3.5 x 10-8 mol/l | pH 5; Tan: 25 ° C | (1) ACD |
| Posesyon | Valè | Kondisyon | Sous |
| Solubilite molè | 3.5 x 10-8 mol/l | pH 6; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 3.6 x 10-8 mol/l | pH 7; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 4.0 x 10-8 mol/l | pH 8; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 8.1 x 10-8 mol/l | pH 9; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 4.5 x 10-7 mol/l | pH 10; Tan: 25 ° C | (1) ACD |
| Solubilite molè | 3.6 x 10-8 mol/l | PH dlo unbuffered 7.00; Tan: 25 ° C | (1) ACD |
| Pwa molekilè | 769.96 | ||
| pka | 9.16 ± 0.20 | Pifò asid tanperati: 25 ° C | (1) ACD |
| pka | 1.73 ± 0.10 | Pifò debaz tanperati: 25 ° C | (1) ACD |
(1) Kalkile lè l sèvi avèk avanse Chimi Devlopman (ACD/Labs) lojisyèl v11.02 (© 1994-2023 ACD/Labs)
Densite
| Posesyon | Valè | Kondisyon | Sous |
| Densite | 1.25 ± 0.1 g/cm3 | Tanperati: 20 ° C; Peze: 760 Torr | (1) ACD |
| Volim molè | 615.5 ± 7.0 cm3/mol | Tanperati: 20 ° C; Peze: 760 Torr | (1) ACD |
(1) Kalkile lè l sèvi avèk avanse Chimi Devlopman (ACD/Labs) lojisyèl v11.02 (© 1994-2023 ACD/Labs)
Lipinski
| Posesyon | Valè | Kondisyon | Sous |
| Lib lib wotasyon | 14 | (1) ACD | |
| H akseptab | 13 | (1) ACD | |
| H donatè | 3 | (1) ACD | |
| H donatè/aksepte sòm | 16 | (1) ACD | |
| logp | 7.710 ± 0.709 | Tan: 25 ° C | (1) ACD |
| Pwa molekilè | 769.96 |
(1) Kalkile lè l sèvi avèk avanse Chimi Devlopman (ACD/Labs) lojisyèl v11.02 (© 1994-2023 ACD/Labs)
Estrikti ki gen rapò
| Posesyon | Valè | Kondisyon | Sous |
| Zòn sifas polè | 155 A2 | (1) ACD | |
(1) Kalkile lè l sèvi avèk avanse Chimi Devlopman (ACD/Labs) lojisyèl v11.02 (© 1994-2023 ACD/Labs)
Spèktr ki disponib
1H NMR
13c NMR
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