![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI, ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI, ACI) Imaj ki prezante](https://cdn.globalso.com/nvchem/118-Re36H44N2O8Si-Uridine.jpg)
118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI, ACI)
| Pwopriyete fizik kle yo | Valè | Kondisyon |
| Pwa molekilè | 660,83 | - |
| Dansite (Prevwa) | 1.24±0.1 g/cm3 | Tanperati: 20 °C; Press: 760 Torr |
| pKa (Prevwa) | 9.39±0.10 | Tanperati ki pi asid: 25 °C |
Canonical SMILES O=C1C=CN(C(=O)N1)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C= C5)C(O)C2O[Si](C)(C)C(C)(C)C
Souri izomerik
C(OC[C@H]1O[C@H]([C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O)N2C( =O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
InChI
InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-31(40)29(45-33(32) )38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13- 17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3, (H,37,39,41)/t29-,31-,32-,33-/m1/s1
InChI kle
KVHQIELPHWJPSY-WXQJYUTRSA-N
2 Lòt Non pou sibstans sa a
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]uridine (ACI); 2′-O-tert-Butyldimethylsilyl-5′-O-(4,4′-dimethoxytrityl)uridine
Spectre ki disponib
1H RMN
13C RMN
Etero RMN
Mass
| Pwopriyete ki disponib |
| Byolojik |
| Chimik |
| Dansite |
| Lipinski |
| Estrikti ki gen rapò |
Byolojik
| Pwopriyete | Valè | Kondisyon | Sous |
| Faktè byokonsantrasyon | 2.21 x 105 | pH 1; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.21 x 105 | pH 2; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.21 x 105 | pH 3; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.21 x 105 | pH 4; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.21 x 105 | pH 5; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.21 x 105 | pH 6; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.20 x 105 | pH 7; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 2.12 x 105 | pH 8; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 1.54 x 105 | pH 9; Tanperati: 25 °C | (1) ACD |
| Faktè byokonsantrasyon | 42500 | pH 10; Tanperati: 25 °C | (1) ACD |
(1) Kalkile avèk lojisyèl Devlopman Chimi Avanse (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs)
Chimik
| Pwopriyete | Valè | Kondisyon | Sous |
| Koc | 2.33 x 105 | pH 1; Tanperati: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 2; Tanperati: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 3; Tanperati: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 4; Tanperati: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 5; Tanperati: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 6; Tanperati: 25 °C | (1) ACD |
| Pwopriyete | Valè | Kondisyon | Sous |
| Koc | 2.32 x 105 | pH 7; Tanperati: 25 °C | (1) ACD |
| Koc | 2.23 x 105 | pH 8; Tanperati: 25 °C | (1) ACD |
| Koc | 1.62 x 105 | pH 9; Tanperati: 25 °C | (1) ACD |
| Koc | 44800 | pH 10; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 1; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 2; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 3; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 4; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 5; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 6; Tanperati: 25 °C | (1) ACD |
| logD | 7.33 | pH 7; Tanperati: 25 °C | (1) ACD |
| logD | 7.32 | pH 8; Tanperati: 25 °C | (1) ACD |
| logD | 7.18 | pH 9; Tanperati: 25 °C | (1) ACD |
| logD | 6.62 | pH 10; Tanperati: 25 °C | (1) ACD |
| logP | 7.334±0.643 | Tanperati: 25 °C | (1) ACD |
| Mass Intrinsèque Solibilite | 3.5 x 10-5 g/L | Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 1; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 2; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 3; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 4; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 5; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 6; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | pH 7; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.6 x 10-5 g/L | pH 8; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 5.0 x 10-5 g/L | pH 9; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 1.9 x 10-4 g/L | pH 10; Tanperati: 25 °C | (1) ACD |
| Solibilite mas | 3.5 x 10-5 g/L | Dlo san tampon pH 7.00; Tanperati: 25 °C | (1) ACD |
| Solibilite intrinsèque molè | 5.3 x 10-8 mol/L | Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 1; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 2; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 3; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 4; Tanperati: 25 °C | (1) ACD |
| Pwopriyete | Valè | Kondisyon | Sous |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 5; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 6; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | pH 7; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.5 x 10-8 mol/L | pH 8; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 7.6 x 10-8 mol/L | pH 9; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 2.8 x 10-7 mol/L | pH 10; Tanperati: 25 °C | (1) ACD |
| Solibilite molè | 5.3 x 10-8 mol/L | Dlo san tampon pH 7.00; Tanperati: 25 °C | (1) ACD |
| Pwa molekilè | 660,83 | ||
| pKa | 9.39±0.10 | Tanperati ki pi asid: 25 °C | (1) ACD |
(1) Kalkile avèk lojisyèl Devlopman Chimi Avanse (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs)
Dansite
| Pwopriyete | Valè | Kondisyon | Sous |
| Dansite | 1.24±0.1 g/cm3 | Tanperati: 20 °C; Press: 760 Torr | (1) ACD |
| Volim molè | 528.8±5.0 cm3/mol | Tanperati: 20 °C; Press: 760 Torr | (1) ACD |
(1) Kalkile avèk lojisyèl Devlopman Chimi Avanse (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs)
Lipinski
| Pwopriyete | Valè | Kondisyon | Sous |
| Obligasyon ki ka vire lib | 13 | (1) ACD | |
| H Aseptè | 10 | (1) ACD | |
| H Donatè | 2 | (1) ACD | |
| H Sòm donatè/akseptè | 12 | (1) ACD | |
| logP | 7.334±0.643 | Tanperati: 25 °C | (1) ACD |
| Pwa molekilè | 660,83 |
(1) Kalkile avèk lojisyèl Devlopman Chimi Avanse (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs)
Estrikti ki gen rapò
| Pwopriyete | Valè | Kondisyon | Sous |
| Zòn Sifas Polè | 116 A2 | (1) ACD | |
(1) Kalkile avèk lojisyèl Devlopman Chimi Avanse (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs)
Spectre ki disponib
1H RMN
13C RMN
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